Blood is mostly composed of innumerable red blood corpuscles and white blood corpuscles embedded in straw colored liquid base called plasma. The life span of these blood corpuscles is approximately four months. Blood corpuscles are constantly manufactured in the hollow space inside the bones called bone marrow. The old blood corpuscles disintegrate after four months and the new corpuscles take up their place. Hence people can donate blood at regular intervals. The red blood corpuscles contain hemoglobin – an important constituent that is responsible for transporting oxygen to the various cells in the human body.
Thallesemia is a
genetic disease wherein the hemoglobin structure is defective. The cause of this
defect lies with the genes/chromosomes of this individual.
is of two types:
Thallesemia trait (minor): In this case only one of the two genes responsible for production of hemoglobin is defective.
major: In this case both the genes are defective.
major is an extremely serious disease. It is very prevalent in India. Every year
more than 7000 thallesemia major children are born in India, whereas there are
more than 1,00,000 such children born in the world.
In case of thallesemia trait the person’s health and life in general is normal. Only when both the parents are thallesemia minors is there a possibility of their child being a thallesemia major. In case only one of the parent has thallesemia trait there is no possibility of the child being thallesemia major.
Toprani Advanced Lab Systems, 2005
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