Auto antibodies available in this profile:
These are done by Immunoblot assay.
Antibodies, which may also help but not, included in
this profile are –
ASMA (smooth muscle antibody) and
These are done by
IFA. These are requested separately or as extended profile
These are requested separately or as extended profile
Autoimmune diseases of the liver include
Autoimmune Hepatitis (AIH),
Primary Biliary Liver Cirrhosis (PBC) and
Primary Sclerosing Cholangitis (PSC).
Following antibodies are generally found in Autoimmune hepatitis
SMA, p-ANCA anti-SLA/LP
Mitochondrial antibodies - AMA- M 2 are directed against proteins of the inner
and outer mitochondrial membrane. They are a highly sensitive and specific
marker of primary Biliary cirrhosis (PBC).
Most patients with Primary Sclerosing Cholangitis
display auto antibodies against granulocytes (p-ANCA). Occasionally, p-ANCA can
also occur in AIH and PBC, and their value for the differential diagnosis is
limited in this respect. Even though overlaps between PSC and AIH have been
reported, antibodies against SLA/LP have not been found in such patients.
| Serum, 2 ml - collect 3 to 4ml.
of blood in plain bulb
| 1 week
Technical details available from the lab on request.
Toprani Advanced Lab Systems, 2005
Suflam Appt, 10 Haribhakti Colony, Racecourse, Vadodara - Guj 390007 India
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